:root {
            --primary: #2c6fbb;
            --primary-dark: #1d5a9c;
            --secondary: #4cc9f0;
            --accent: #ff6b6b;
            --light: #f8f9fa;
            --dark: #212529;
            --gray: #6c757d;
            --success: #28a745;
            --error: #dc3545;
            --warning: #ffc107;
            --card-shadow: 0 10px 30px rgba(0, 0, 0, 0.08);
            --transition: all 0.3s ease;
            --bio-gradient: linear-gradient(135deg, #2c6fbb 0%, #4cc9f0 100%);
        }



        .bio-container {
            max-width: 750px;
            margin: auto;
            background: white;
            border-radius: 16px;
            overflow: hidden;
            box-shadow: var(--card-shadow);
        }

        .bio-app-header {
            background: var(--bio-gradient);
            color: white;
            padding: 25px 30px;
            position: relative;
            overflow: hidden;
        }

        .bio-app-header::before {
            content: "";
            position: absolute;
            top: -50%;
            right: -50%;
            width: 200%;
            height: 200%;
            background: radial-gradient(circle, rgba(255,255,255,0.1) 0%, rgba(255,255,255,0) 70%);
            transform: rotate(30deg);
        }

        .bio-header-content {
            position: relative;
            z-index: 2;
            width: 100%;
            display: flex;
            justify-content: space-between;
            align-items: center;
            flex-wrap: wrap;
            gap: 20px;
        }

        .bio-app-title {
            display: flex;
            flex-direction: column;
			align-content: center;
    		flex-wrap: wrap;
        }

        .bio-app-header h2 {
            font-size: 2rem;
            font-weight: 600;
            margin: 0;
            display: flex;
            align-items: center;
            gap: 12px;
        }

        .bio-app-header h2 i {
            font-size: 1.8rem;
            background: rgba(255, 255, 255, 0.2);
            padding: 10px;
            border-radius: 12px;
        }

        .bio-app-description {
            font-size: 1rem;
            font-weight: 300;
            opacity: 0.9;
            margin-top: 8px;
            max-width: 600px;
        }

        .bio-header-right {
            display: flex;
            align-items: center;
            gap: 15px;
        }

        .bio-app-body {
            padding: 30px;
        }

        .bio-tabs-container {
            margin-bottom: 30px;
            background: #f8fafc;
            border-radius: 12px;
            padding: 5px;
        }

        .bio-tab-buttons {
            display: flex;
            gap: 8px;
            flex-wrap: wrap;
        }

        .bio-tab-button {
            background: white;
            border: none;
            padding: 12px 24px;
            cursor: pointer;
            font-size: 1rem;
            font-weight: 500;
            color: var(--gray);
            border-radius: 8px;
            transition: var(--transition);
            display: flex;
            align-items: center;
            gap: 8px;
            flex: 1;
            justify-content: center;
            text-align: center;
            box-shadow: 0 2px 5px rgba(0,0,0,0.05);
        }

        .bio-tab-button:hover {
            color: var(--primary);
            box-shadow: 0 4px 8px rgba(0,0,0,0.08);
        }

        .bio-tab-button.active {
            background: var(--primary);
            color: white;
            box-shadow: 0 4px 12px rgba(44, 111, 187, 0.25);
        }

        .bio-tab-content {
            display: none;
            animation: fadeIn 0.4s ease;
            padding: 15px 0px 0px 15px;
        }

        @keyframes fadeIn {
            from { opacity: 0; transform: translateY(10px); }
            to { opacity: 1; transform: translateY(0); }
        }

        .bio-tab-content.active {
            display: block;
        }

        .bio-input-section {
            margin-bottom: 25px;
        }

        .bio-section-title {
            display: flex;
            align-items: center;
            gap: 10px;
            font-size: 1.1rem;
            font-weight: 600;
            color: var(--dark);
            margin-bottom: 15px;
        }

        .bio-section-title i {
            color: var(--primary);
            font-size: 1.2rem;
        }

        textarea#dataPaste {
            width: -webkit-fill-available;
            min-height: 200px;
            padding: 20px;
            border: 2px dashed #d1d9e6;
            border-radius: 12px;
            font-family: 'Roboto Mono', monospace;
            font-size: 0.95rem;
            transition: var(--transition);
            background: #fafcff;
            resize: vertical;
        }

        textarea#dataPaste:focus {
            outline: none;
            border-color: var(--primary);
            box-shadow: 0 0 0 4px rgba(44, 111, 187, 0.15);
        }

        textarea#dataPaste.drag-over {
            border-color: var(--primary);
            background: rgba(44, 111, 187, 0.05);
        }

        .bio-input-hint {
            font-size: 0.9rem;
            color: var(--gray);
            margin-top: 8px;
            display: flex;
            align-items: center;
            gap: 8px;
        }

        .bio-file-upload-area {
            border: 2px dashed #d1d9e6;
            border-radius: 12px;
            padding: 30px;
            text-align: center;
            background: #fafcff;
            transition: var(--transition);
            cursor: pointer;
            margin-bottom: 15px;
        }

        .bio-file-upload-area:hover, .bio-file-upload-area.drag-over {
            border-color: var(--primary);
            background: rgba(44, 111, 187, 0.05);
        }

        .bio-file-upload-area i {
            font-size: 2.5rem;
            color: var(--primary);
            margin-bottom: 15px;
        }

        .bio-file-upload-text {
            font-size: 1.1rem;
            font-weight: 500;
            margin-bottom: 10px;
            color: var(--dark);
        }

        .bio-file-upload-subtext {
            font-size: 0.9rem;
            color: var(--gray);
            margin-bottom: 15px;
        }

        .bio-file-input {
            display: none;
        }

        .bio-file-name-display {
            font-size: 0.95rem;
            padding: 12px 20px;
            background: #f0f7ff;
            border-radius: 10px;
            display: inline-flex;
            align-items: center;
            gap: 10px;
            color: var(--primary-dark);
            font-weight: 500;
        }

        /* New styles for format dropdowns */
        .bio-format-selection {
            display: flex;
            gap: 15px;
            margin-top: 20px;
            flex-wrap: wrap;
            margin-bottom: 20px;
        }

        .bio-format-selection > div {
            flex: 1;
            min-width: 200px;
        }

        .bio-format-selection label {
            display: block;
            font-size: 0.95rem;
            font-weight: 500;
            color: var(--dark);
            margin-bottom: 8px;
        }

        .bio-format-selection select {
            width: 100%;
            padding: 12px 15px;
            border: 2px solid #d1d9e6;
            border-radius: 12px;
            font-size: 1rem;
            background-color: white;
            appearance: none; /* Remove default arrow */
            -webkit-appearance: none;
            -moz-appearance: none;
            background-image: url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 24 24' fill='%236c757d'%3E%3Cpath d='M7 10l5 5 5-5z'/%3E%3C/svg%3E");
            background-repeat: no-repeat;
            background-position: right 15px center;
            background-size: 18px;
            transition: var(--transition);
        }

        .bio-format-selection select:focus {
            outline: none;
            border-color: var(--primary);
            box-shadow: 0 0 0 4px rgba(44, 111, 187, 0.15);
        }
        
        .bio-btn {
            padding: 14px 28px;
            border: none;
            border-radius: 12px;
            font-size: 1rem;
            font-weight: 500;
            cursor: pointer;
            transition: var(--transition);
            display: inline-flex;
            align-items: center;
            justify-content: center;
            gap: 10px;
        }

        .bio-btn-primary {
            background: var(--primary);
            color: white;
            box-shadow: 0 4px 14px rgba(44, 111, 187, 0.35);
        }

        .bio-btn-primary:hover {
            background: var(--primary-dark);
            transform: translateY(-2px);
            box-shadow: 0 6px 18px rgba(44, 111, 187, 0.45);
        }

        .bio-btn-secondary {
            background: white;
            color: var(--primary);
            border: 2px solid #d1d9e6;
        }

        .bio-btn-secondary:hover {
            background: #f8fbff;
            border-color: var(--primary);
        }
        
        .bio-btn-icon {
            font-size: 1.1rem;
        }

        .bio-action-buttons {
            margin: 30px 0;
            display: flex;
            gap: 15px;
            flex-wrap: wrap;
			justify-content: center;
        }

        .bio-spinner-container {
            display: flex;
            justify-content: center;
            padding: 30px;
            display: none;
        }

        .bio-spinner {
            width: 50px;
            height: 50px;
            border: 5px solid rgba(44, 111, 187, 0.2);
            border-top: 5px solid var(--primary);
            border-radius: 50%;
            animation: spin 1s linear infinite;
        }

        @keyframes spin {
            0% { transform: rotate(0deg); }
            100% { transform: rotate(360deg); }
        }

        .bio-results-container {
            margin-top: 30px;
            animation: fadeIn 0.5s ease;
            display: none;
        }

        .bio-results-header {
            display: flex;
            justify-content: space-between;
            align-items: center;
            margin-bottom: 20px;
            flex-wrap: wrap;
            gap: 15px;
        }

        .bio-results-title {
            font-size: 1.5rem;
            font-weight: 600;
            color: var(--dark);
            display: flex;
            align-items: center;
            gap: 10px;
        }

        .bio-results-actions {
            display: flex;
            gap: 12px;
        }

        .bio-btn-sm {
            padding: 10px 20px;
            font-size: 0.95rem;
        }

        .bio-results-content {
            background: #f8faff;
            border-radius: 12px;
            border: 2px solid #e6f0ff;
            padding: 20px;
            overflow: auto;
            max-height: 500px;
        }

        pre#results {
            white-space: pre-wrap;
            word-break: break-word;
            font-family: 'Roboto Mono', monospace;
            font-size: 0.9rem;
            line-height: 1.5;
        }

        .bio-app-footer {
            padding: 20px 30px;
            border-top: 1px solid #eaeaea;
            text-align: center;
            color: var(--gray);
            font-size: 0.9rem;
        }

        .bio-footer-link {
            color: var(--primary);
            text-decoration: none;
        }

        .bio-notification {
            position: fixed; 
            bottom: -100px;
            left: 50%; 
            transform: translateX(-50%);
            padding: 15px 25px;
            border-radius: 8px;
            box-shadow: 0 4px 15px rgba(0, 0, 0, 0.2);
            color: white;
            display: flex;
            align-items: center;
            gap: 10px;
            z-index: 1000; 
            transition: bottom 0.5s cubic-bezier(0.175, 0.885, 0.32, 1.275);
            opacity: 0;
        }

        .bio-notification.show {
            opacity: 1;
            bottom: 30px;
        }

        .bio-notification.info {
            background: var(--primary);
        }

        .bio-notification.success {
            background: var(--success);
        }

        .bio-notification.error {
            background: var(--error);
        }

        .bio-notification.warning {
            background: var(--warning);
            color: var(--dark);
        }

        /* Responsive design */
        @media (max-width: 768px) {
            .bio-container {
                margin: 10px auto;
            }
            
            .bio-app-body {
                padding: 20px;
            }
            
            .bio-header-content {
                flex-direction: column;
                align-items: flex-start;
            }
            
            .bio-id-input-container {
                flex-direction: column;
            }
            
            .bio-id-input-container input {
                min-width: 100%;
            }
            
            .bio-action-buttons {
                flex-direction: column;
            }
            
            .bio-results-header {
                flex-direction: column;
                align-items: flex-start;
            }
            
            .bio-results-actions {
                width: 100%;
                justify-content: flex-end;
            }
            

            .bio-format-selection {
                flex-direction: column;
            }
            .bio-tab-content{
                padding: 5px;
            }
        }

        @media (max-width: 480px) {
            .bio-app-header {
                padding: 20px;
            }
            
            .bio-app-header h2 {
                font-size: 1.5rem;
            }
            
            .bio-app-description {
                font-size: 0.9rem;
            }
            
            .bio-btn {
                width: 100%;
                justify-content: center;
            }
			.bio-tab-button {
				padding:10px 6px;
			}
			.bio-section-title{
				display: none;
			}
			.bio-input-section {
				margin-top: 35px;
			}
            
            textarea#dataPaste {
                min-height: 150px;
                padding: 15px;
            }
        }
        /* ===== Progress UI ===== */
    .bio-progress-container {
      display: none;
      margin-top: 1em;
      width: 100%;
      max-width: 400px;
    }
    .bio-progress-bar {
      width: 0%;
      height: 1em;
      background-color: #3b82f6;
      border-radius: 0.25em;
      transition: width 0.5s ease-out;
    }
    .bio-progress-track {
      width: 100%;
      background-color: #e5e7eb;
      border-radius: 0.25em;
      overflow: hidden;
    }
    #time-remaining {
      display: block;
      margin-top: 0.5em;
      font-size: 0.9em;
      color: #374151;
	  text-align: right;
      font-weight: bold;
    }
    select#uploadInputFormat {
    height: auto;
}
select#uploadOutputFormat {
    height: auto;
}
select#uploadMoleculeType{  
        height: auto;

}
button#convertBtn:before {
    content: "\f085";
    font-family: 'FontAwesome';
    font-size: 1.3rem;
}
.bio-format-selection select {
height: auto;   
}